Won Taek Lee Selected Research

Agmatine

12/2017	Endogenous Agmatine Induced by Ischemic Preconditioning Regulates Ischemic Tolerance Following Cerebral Ischemia.
7/2015	Agmatine Attenuates Brain Edema and Apoptotic Cell Death after Traumatic Brain Injury.
8/2014	Retroviral expression of human arginine decarboxylase reduces oxidative stress injury in mouse cortical astrocytes.
5/2014	Agmatine improves cognitive dysfunction and prevents cell death in a streptozotocin-induced Alzheimer rat model.
1/2013	The multifaceted effects of agmatine on functional recovery after spinal cord injury through Modulations of BMP-2/4/7 expressions in neurons and glial cells.
12/2012	Protective effects of agmatine on lipopolysaccharide-injured microglia and inducible nitric oxide synthase activity.
12/2011	Agmatine-reduced collagen scar area accompanied with surface righting reflex recovery after complete transection spinal cord injury.
2/2011	Effects of agmatine on hypoxic microglia and activity of nitric oxide synthase.
9/2010	Regulation of endothelial nitric oxide synthase by agmatine after transient global cerebral ischemia in rat brain.
8/2010	Endogenous agmatine inhibits cerebral vascular matrix metalloproteinases expression by regulating activating transcription factor 3 and endothelial nitric oxide synthesis.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Won Taek Lee Research Topics

Disease

6	Wounds and Injuries (Trauma) 08/2014 - 07/2009
5	Hypoxia (Hypoxemia) 01/2015 - 02/2011
4	Ischemic Stroke 10/2021 - 01/2015
4	Brain Ischemia (Cerebral Ischemia) 02/2019 - 05/2010
4	Spinal Cord Injuries (Spinal Cord Injury) 01/2015 - 12/2011
4	Ischemia 09/2010 - 03/2004
3	Neuroinflammatory Diseases 10/2021 - 03/2010
3	Brain Edema (Cerebral Edema) 12/2017 - 05/2010
3	Brain Injuries (Brain Injury) 01/2015 - 12/2013
3	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2015 - 05/2010
3	Stroke (Strokes) 01/2014 - 03/2010
2	Edema (Dropsy) 07/2015 - 01/2015
2	Central Nervous System Diseases (CNS Diseases) 07/2015 - 05/2014
2	Reperfusion Injury 01/2015 - 10/2007
2	Cognitive Dysfunction 05/2014 - 01/2014
1	Hyperglycemia 01/2022
1	Infarction (Infarctions) 12/2017
1	Traumatic Brain Injuries (Traumatic Brain Injury) 07/2015
1	Neuroblastoma 01/2015
1	Alzheimer Disease (Alzheimer's Disease) 01/2014
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2014
1	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 01/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2014
1	Hypertension (High Blood Pressure) 01/2014
1	Atherosclerosis 01/2014
1	Inflammation (Inflammations) 12/2013
1	Encephalitis (Encephalitis, Rasmussen) 12/2013
1	Cicatrix (Scar) 12/2011
1	Neoplasms (Cancer) 11/2011
1	Cerebral Palsy (Spastic Diplegia) 04/2011
1	Diabetic Nephropathies (Diabetic Nephropathy) 12/2010
1	Nephrotic Syndrome (Syndrome, Nephrotic) 12/2010
1	Diabetes Mellitus 12/2010
1	Brain Infarction 03/2010
1	Infections 03/2010
1	Transient Ischemic Attack 03/2010
1	Hypersensitivity (Allergy) 03/2007

Drug/Important Bio-Agent (IBA)

14	AgmatineIBA 12/2017 - 10/2007
4	arginine decarboxylaseIBA 12/2017 - 05/2010
4	Matrix Metalloproteinases (MMPs)IBA 09/2010 - 03/2004
3	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 10/2007
3	CytokinesIBA 10/2021 - 03/2010
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2017 - 10/2007
3	Aquaporins (Water Channels)IBA 07/2015 - 05/2010
3	Proteins (Proteins, Gene)FDA Link 01/2015 - 12/2010
3	Neuroprotective AgentsIBA 05/2014 - 02/2011
2	Oxygen (Dioxygen)IBA 02/2019 - 10/2007
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2015 - 09/2014
2	Arginine (L-Arginine)FDA Link 08/2014 - 05/2010
2	MAP Kinase Kinase Kinase 5IBA 01/2014 - 12/2013
2	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 09/2010 - 10/2007
1	Interleukin-13IBA 10/2021
1	Interleukin-4 (Interleukin 4)IBA 10/2021
1	Conditioned Culture MediaIBA 02/2017
1	Mitogen-Activated Protein KinasesIBA 07/2015
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2015
1	cresyl violetIBA 01/2015
1	Disks Large Homolog 4 ProteinIBA 01/2015
1	SynaptophysinIBA 01/2015
1	Caspase 3 (Caspase-3)IBA 01/2015
1	N- (2- (4- bromocinnamylamino)ethyl)- 5- isoquinolinesulfonamide (h89)IBA 01/2015
1	Nerve Growth Factors (Neurotrophins)IBA 01/2015
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2015
1	Phenol (Carbolic Acid)FDA Link 09/2014
1	Transcription Factors (Transcription Factor)IBA 09/2014
1	ResveratrolIBA 09/2014
1	Interleukin-10 (Interleukin 10)IBA 09/2014
1	AntioxidantsIBA 09/2014
1	PolyaminesIBA 08/2014
1	Neurotransmitter Agents (Neurotransmitter)IBA 08/2014
1	Receptor for Advanced Glycation End ProductsIBA 07/2014
1	LigandsIBA 07/2014
1	Streptozocin (Streptozotocin)FDA Link 05/2014
1	Vasodilator Agents (Vasodilators)IBA 01/2014
1	MelatoninIBA 01/2014
1	Insulin (Novolin)FDA Link 01/2014
1	AdiponectinIBA 01/2014
1	SolutionsIBA 12/2013
1	p38 Mitogen-Activated Protein KinasesIBA 12/2013
1	Interleukin-1beta (Interleukin 1 beta)IBA 12/2013
1	Transforming Growth Factors (Transforming Growth Factor)IBA 12/2011
1	Pharmaceutical PreparationsIBA 12/2011
1	Bone Morphogenetic Protein 7IBA 12/2011
1	CollagenIBA 12/2011
1	Propidium (Propidium Iodide)IBA 11/2011
1	NitritesIBA 02/2011
1	AlbuminsIBA 12/2010
1	OsteopontinIBA 12/2010
1	Blood Glucose (Blood Sugar)IBA 12/2010
1	CholesterolIBA 12/2010
1	Capsaicin (Zostrix)FDA Link 03/2007
1	Molecular Chaperones (Chaperone, Molecular)IBA 03/2004
1	Serine Proteases (Serine Protease)IBA 03/2004
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 03/2004
1	Dizocilpine Maleate (Dizocilpine)IBA 06/2002
1	Morphine (MS Contin)FDA LinkGeneric 06/2002

Therapy/Procedure

3	Therapeutics 02/2019 - 04/2011
1	Transplantation 01/2015
1	Ligation 03/2007
1	Rhizotomy 03/2007